Sensitized cells come of age: a new era in renal immunology with important therapeutic implications

WG Couser - Journal of the American Society of Nephrology, 1999 - journals.lww.com
This article is the first in a new effort by the editors of JASN to translate results of basic
research published in the Journal into information of relevance to the clinical nephrologist.
So why should the clinician be interested in the observations of Cunningham et al. in this
issue, that a small series of patients with anti-neutrophil cytoplasmic antibody (ANCA)-
positive crescentic rapidly progressive glomerulonephritis (RPGN) exhibit features of
delayed-type hypersensitivity in their biopsies (T cells, macrophages, tissue factor, and …