Early development of Ig-secreting cells in young of germ-free BALB/c mice fed a chemically defined ultrafiltered diet
NA Bos, CG Meeuwsen, H Hooijkaas, R Benner… - Cellular …, 1987 - Elsevier
The influence of antigenic stimulation on the early development of the “spontaneously”
occurring (“background”) IgM-, IgG-, and IgA-secreting cells has been studied in mice. To
evaluate the effect of such exogenous stimulation by an evolving microbial microflora. the
young of BALB/c mice that were kept under germ-free conditions and fed a low molecular
weight chemically defined synthetic diet (GF-CD) were compared with the young of
conventional BALB/c mice fed natural ingredients (CV-NI). The young were first suckling …
occurring (“background”) IgM-, IgG-, and IgA-secreting cells has been studied in mice. To
evaluate the effect of such exogenous stimulation by an evolving microbial microflora. the
young of BALB/c mice that were kept under germ-free conditions and fed a low molecular
weight chemically defined synthetic diet (GF-CD) were compared with the young of
conventional BALB/c mice fed natural ingredients (CV-NI). The young were first suckling …