Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG …
M Roach III, G Hanks, H Thames Jr… - International Journal of …, 2006 - Elsevier
In 1996 the American Society for Therapeutic Radiology and Oncology (ASTRO) sponsored
a Consensus Conference to establish a definition of biochemical failure after external beam
radiotherapy (EBRT). The ASTRO definition defined prostate specific antigen (PSA) failure
as occurring after three consecutive PSA rises after a nadir with the date of failure as the
point halfway between the nadir date and the first rise or any rise great enough to provoke
initiation of therapy. This definition was not linked to clinical progression or survival; it …
a Consensus Conference to establish a definition of biochemical failure after external beam
radiotherapy (EBRT). The ASTRO definition defined prostate specific antigen (PSA) failure
as occurring after three consecutive PSA rises after a nadir with the date of failure as the
point halfway between the nadir date and the first rise or any rise great enough to provoke
initiation of therapy. This definition was not linked to clinical progression or survival; it …