Transient leukaemia–a benign form of leukaemia in newborn infants with trisomy 21.

A Zipursky - British journal of haematology, 2003 - search.ebscohost.com
A Zipursky
British journal of haematology, 2003search.ebscohost.com
Review Page 1 Review TRANSIENT LEUKAEMIA – A BENIGN FORM OF LEUKAEMIA IN
NEWBORN INFANTS WITH TRISOMY 21 Transient Leukaemia (TL) occurs frequently in
newborn infants with Down Syndrome. Because in most cases the disease disappears
spontaneously, it has been difficult to accept it as leukaemia, and as a result it has been referred
by a variety of names including Transient Myeloproliferative Disorder and Transient Abnormal
Myelopoiesis, suggesting that it is not leukaemia. In this review I shall present evidence that the …
Abstract
Provides information on transient leukemia which occurs frequently in newborn infants with Down Syndrome. Terms used in referring to the disease; Evidence that the disease is considered leukemia; Nature of leukemic cells and its association with trisomy 21.
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