An emerging role for endothelial nitric oxide synthase in chronic inflammation and cancer
L Ying, LJ Hofseth - Cancer research, 2007 - AACR
L Ying, LJ Hofseth
Cancer research, 2007•AACRNitric oxide (NO) is a free radical that is involved in carcinogenesis. Recent literature
indicates that endothelial NO synthase (eNOS) can modulate cancer-related events
(angiogenesis, apoptosis, cell cycle, invasion, and metastasis). We review the literature
linking eNOS to carcinogenesis to encourage future research assessing the role of eNOS in
cancer prevention and treatment.[Cancer Res 2007; 67 (4): 1407–10]
indicates that endothelial NO synthase (eNOS) can modulate cancer-related events
(angiogenesis, apoptosis, cell cycle, invasion, and metastasis). We review the literature
linking eNOS to carcinogenesis to encourage future research assessing the role of eNOS in
cancer prevention and treatment.[Cancer Res 2007; 67 (4): 1407–10]
Abstract
Nitric oxide (NO) is a free radical that is involved in carcinogenesis. Recent literature indicates that endothelial NO synthase (eNOS) can modulate cancer-related events (angiogenesis, apoptosis, cell cycle, invasion, and metastasis). We review the literature linking eNOS to carcinogenesis to encourage future research assessing the role of eNOS in cancer prevention and treatment. [Cancer Res 2007;67(4):1407–10]
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