Cannabinoids: potential anticancer agents

M Guzman - Nature reviews cancer, 2003 - nature.com
M Guzman
Nature reviews cancer, 2003nature.com
Cannabinoids—the active components of Cannabis sativa and their derivatives—exert
palliative effects in cancer patients by preventing nausea, vomiting and pain and by
stimulating appetite. In addition, these compounds have been shown to inhibit the growth of
tumour cells in culture and animal models by modulating key cell-signalling pathways.
Cannabinoids are usually well tolerated, and do not produce the generalized toxic effects of
conventional chemotherapies. So, could cannabinoids be used to develop new anticancer …
Abstract
Cannabinoids — the active components of Cannabis sativa and their derivatives — exert palliative effects in cancer patients by preventing nausea, vomiting and pain and by stimulating appetite. In addition, these compounds have been shown to inhibit the growth of tumour cells in culture and animal models by modulating key cell-signalling pathways. Cannabinoids are usually well tolerated, and do not produce the generalized toxic effects of conventional chemotherapies. So, could cannabinoids be used to develop new anticancer therapies?
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