Brain blood flow changes in depressed patients treated with interpersonal psychotherapy or venlafaxine hydrochloride: preliminary findings
SD Martin, E Martin, SS Rai… - Archives of general …, 2001 - jamanetwork.com
Background Functional brain imaging studies in major depression have suggested
abnormalities of areas, including the frontal cortex, cingulate gyrus, basal ganglia, and
temporal cortex. We hypothesized that venlafaxine hydrochloride and interpersonal
psychotherapy (IPT) might each alter brain blood flow in some or all of these areas on
sequential single photon emission computed tomography (SPECT) scans. Methods Twenty-
eight men and women aged 30 to 53 years with aDSM-IVmajor depressive episode, a 17 …
abnormalities of areas, including the frontal cortex, cingulate gyrus, basal ganglia, and
temporal cortex. We hypothesized that venlafaxine hydrochloride and interpersonal
psychotherapy (IPT) might each alter brain blood flow in some or all of these areas on
sequential single photon emission computed tomography (SPECT) scans. Methods Twenty-
eight men and women aged 30 to 53 years with aDSM-IVmajor depressive episode, a 17 …