Parvalbumin neurons in the entorhinal cortex of subjects diagnosed with bipolar disorder or schizophrenia
H Pantazopoulos, N Lange, RJ Baldessarini… - Biological …, 2007 - Elsevier
BACKGROUND: Growing evidence indicates that the entorhinal cortex (ECx) might be
affected in schizophrenia (SZ) and bipolar disorder (BD). To test whether distinct
interneuronal subpopulations might be altered, numbers of parvalbumin-immunoreactive
(PVB-IR) neurons were measured in the ECx of BD and SZ subjects. These neurons play a
pivotal role within ECx intrinsic circuits. METHODS: Numbers, numerical density, and soma
size of PVB-IR neurons were measured in the ECx of normal control (n= 16), BD (n= 10) …
affected in schizophrenia (SZ) and bipolar disorder (BD). To test whether distinct
interneuronal subpopulations might be altered, numbers of parvalbumin-immunoreactive
(PVB-IR) neurons were measured in the ECx of BD and SZ subjects. These neurons play a
pivotal role within ECx intrinsic circuits. METHODS: Numbers, numerical density, and soma
size of PVB-IR neurons were measured in the ECx of normal control (n= 16), BD (n= 10) …