Context Progressive brain abnormalities in schizophrenia remain controversial. Evidence of
interrelated progressive functional impairment would buttress the case for structural
progression. Mismatch negativity (MMN) is reduced in chronic but not first-hospitalized
schizophrenia and may index progressive structural changes. Objective To determine
whether MMN shows associations with underlying auditory cortex gray matter at first
hospitalization and progressive reduction longitudinally. Design Cross-sectional (first …