The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences

JM Seddon, J Cote, WF Page, SH Aggen… - Archives of …, 2005 - jamanetwork.com
Context Age-related macular degeneration (AMD) is the leading cause of irreversible
blindness among older individuals in many parts of the world. The relative importance of
genes and environment in the etiology of this major public health problem is not well
understood. Objective To investigate the impact of genetic and environmental factors.
Participants Living twins in the National Academy of Sciences–National Research Council
World War II Veteran Twin Registry born between 1917 and 1927. Methods Twins were …