[HTML][HTML] Adenosine A2A receptors play a role in the pathogenesis of hepatic cirrhosis
ESL Chan, MC Montesinos, P Fernandez… - British journal of …, 2006 - ncbi.nlm.nih.gov
ESL Chan, MC Montesinos, P Fernandez, A Desai, DL Delano, H Yee, AB Reiss…
British journal of pharmacology, 2006•ncbi.nlm.nih.govAdenosine is a potent endogenous regulator of inflammation and tissue repair. Adenosine,
which is released from injured and hypoxic tissue or in response to toxins and medications,
may induce pulmonary fibrosis in mice, presumably via interaction with a specific adenosine
receptor. We therefore determined whether adenosine and its receptors contribute to the
pathogenesis of hepatic fibrosis.
which is released from injured and hypoxic tissue or in response to toxins and medications,
may induce pulmonary fibrosis in mice, presumably via interaction with a specific adenosine
receptor. We therefore determined whether adenosine and its receptors contribute to the
pathogenesis of hepatic fibrosis.
Abstract
1. Adenosine is a potent endogenous regulator of inflammation and tissue repair. Adenosine, which is released from injured and hypoxic tissue or in response to toxins and medications, may induce pulmonary fibrosis in mice, presumably via interaction with a specific adenosine receptor. We therefore determined whether adenosine and its receptors contribute to the pathogenesis of hepatic fibrosis.
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