The role of vitamin D in cancer prevention
CF Garland, FC Garland… - … journal of public …, 2006 - ajph.aphapublications.org
CF Garland, FC Garland, ED Gorham, M Lipkin, H Newmark, SB Mohr, MF Holick
American journal of public health, 2006•ajph.aphapublications.orgVitamin D status differs by latitude and race, with residents of the northeastern United States
and individuals with more skin pigmentation being at increased risk of deficiency. A PubMed
database search yielded 63 observational studies of vitamin D status in relation to cancer
risk, including 30 of colon, 13 of breast, 26 of prostate, and 7 of ovarian cancer, and several
that assessed the association of vitamin D receptor genotype with cancer risk. The majority
of studies found a protective relationship between sufficient vitamin D status and lower risk …
and individuals with more skin pigmentation being at increased risk of deficiency. A PubMed
database search yielded 63 observational studies of vitamin D status in relation to cancer
risk, including 30 of colon, 13 of breast, 26 of prostate, and 7 of ovarian cancer, and several
that assessed the association of vitamin D receptor genotype with cancer risk. The majority
of studies found a protective relationship between sufficient vitamin D status and lower risk …
Vitamin D status differs by latitude and race, with residents of the northeastern United States and individuals with more skin pigmentation being at increased risk of deficiency. A PubMed database search yielded 63 observational studies of vitamin D status in relation to cancer risk, including 30 of colon, 13 of breast, 26 of prostate, and 7 of ovarian cancer, and several that assessed the association of vitamin D receptor genotype with cancer risk.
The majority of studies found a protective relationship between sufficient vitamin D status and lower risk of cancer. The evidence suggests that efforts to improve vitamin D status, for example by vitamin D supplementation, could reduce cancer incidence and mortality at low cost, with few or no adverse effects.
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