[HTML][HTML] Resistin is a key mediator of glucose-dependent insulinotropic polypeptide (GIP) stimulation of lipoprotein lipase (LPL) activity in adipocytes
SJ Kim, C Nian, CHS McIntosh - Journal of Biological Chemistry, 2007 - ASBMB
Studies on the physiological roles of the incretin hormone, glucose-dependent insulinotropic
polypeptide (GIP) have largely focused on its insulinotropic action and ability to regulate β-
cell mass. In previous studies on the stimulatory effect of GIP on adipocyte lipoprotein lipase
(LPL), a pathway was identified involving increased phosphorylation of protein kinase B
(PKB) and reduced phosphorylation of LKB1 and AMP-activated protein kinase (AMPK). The
slow time of onset of the responses suggested that GIP may have induced release of an …
polypeptide (GIP) have largely focused on its insulinotropic action and ability to regulate β-
cell mass. In previous studies on the stimulatory effect of GIP on adipocyte lipoprotein lipase
(LPL), a pathway was identified involving increased phosphorylation of protein kinase B
(PKB) and reduced phosphorylation of LKB1 and AMP-activated protein kinase (AMPK). The
slow time of onset of the responses suggested that GIP may have induced release of an …