[HTML][HTML] Polarized expression of Ca2+ channels in pancreatic and salivary gland cells: correlation with initiation and propagation of [Ca2+] i waves
In polarized epithelial cells [Ca 2+] i waves are initiated in discrete regions and propagate
through the cytosol. The structural basis for these compartmentalized and coordinated
events are not well understood. In the present study we used a combination of [Ca 2+] i
imaging at high temporal resolution, recording of Ca 2+-activated Cl− current, and
immunolocalization by confocal microscopy to study the correlation between initiation and
propagation of [Ca 2+] i waves and localization of Ca 2+ release channels in pancreatic …
through the cytosol. The structural basis for these compartmentalized and coordinated
events are not well understood. In the present study we used a combination of [Ca 2+] i
imaging at high temporal resolution, recording of Ca 2+-activated Cl− current, and
immunolocalization by confocal microscopy to study the correlation between initiation and
propagation of [Ca 2+] i waves and localization of Ca 2+ release channels in pancreatic …