[HTML][HTML] Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer
D Haudenschild, T Moseley, L Rose… - Journal of Biological …, 2002 - ASBMB
Members of the interleukin-17 cytokine family are present in a variety of tissues (1-3),
although the founding member, interleukin-17, is expressed exclusively in T cells and B cells
(4-8). The cloning and characterization of a novel single-pass transmembrane protein with
limited homology to the interleukin-17 receptor is reported. High mRNA levels were detected
in prostate, cartilage, kidney, liver, heart, and muscle, whereas transcripts were barely
detected in thymus and leukocytes. At least 11 RNA splice variants were found, transcribed …
although the founding member, interleukin-17, is expressed exclusively in T cells and B cells
(4-8). The cloning and characterization of a novel single-pass transmembrane protein with
limited homology to the interleukin-17 receptor is reported. High mRNA levels were detected
in prostate, cartilage, kidney, liver, heart, and muscle, whereas transcripts were barely
detected in thymus and leukocytes. At least 11 RNA splice variants were found, transcribed …