Retroviral gene delivery

MJ Federspiel, SH Hughes - Methods in cell biology, 1997 - Elsevier
Publisher Summary This chapter describes the properties of retroviruses and the affect of
these properties on the properties of retrovirus-based vectors. In addition, the advantages
and disadvantages of retroviral vectors to those of several other gene transfer techniques
are compared. The chapter describes the retroviral vector system based on the avian
leukosis virus (ALV) retrovirus family. The ALV-based retroviral vector system can be used to
deliver and express genes in avian and mammalian cells in vitro and in vivo. The system …