Expression of monocarboxylate transporter MCT1 in normal and neoplastic human CNS tissues

MK Froberg, DZ Gerhart, BE Enerson, C Manivel… - …, 2001 - journals.lww.com
Expression of monocarboxylate transporter MCT1 was studied in archival tissues from
human CNS using antibodies to the carboxyl-terminal end of MCT1. Sections of neocortex,
hippocampus and cerebellum of brains from 10 adult autopsy patients who died from other
than CNS disease, and from archival surgical biopsy specimens of 83 primary CNS and
eight non-CNS tumors were studied. MCT1 immunoreactivity was present in microvessels
and, ependymocytes of normal CNS tissues similar to that reported for MCT1 expression in …