Exploiting dendritic cells for active immunotherapy of cancer and chronic infection

D O'Neill, N Bhardwaj - Adoptive Immunotherapy: Methods and Protocols, 2005 - Springer
Dendritic cells (DC) are important antigen-presenting cells (APC) that can prime naive T-
cells and control lymphocyte-mediated adaptive immune responses with respect to
magnitude, memory, and self-tolerance. Understanding the biology of these cells is central
to the development of new generation immunotherapies for cancer and chronic infection.
This chapter presents a brief overview of DC biology and the preparation and use of DC-
based vaccines.

[HTML][HTML] Exploiting dendritic cells for active immunotherapy of cancer and chronic infections

DW O'Neill, N Bhardwaj - Molecular biotechnology, 2007 - Springer
Dendritic cells (DCs) are important antigen-presenting cells (APCs) that can prime naive T
cells and control adaptive immune responses with respect to magnitude, memory and self-
tolerance. Understanding the biology of these cells is central to the development of new
generation immunotherapies for cancer and chronic infections. This review presents a brief
overview of DC biology and of the preparation and use of DC-based vaccines.