Gustducin is a taste-cell-specific G protein closely related to the transducins
SK McLaughlin, PJ McKinnon, RF Margolskee - Nature, 1992 - nature.com
SK McLaughlin, PJ McKinnon, RF Margolskee
Nature, 1992•nature.comA novel G protein α-subunit (α-gustducin) has been identified and cloned from taste tissue, α-
Gustducin messenger RNA is expressed in taste buds of all taste papillae (circumvallate,
foliate and fungiform); it is not expressed in non-sensory portions of the tongue, nor is it
expressed in the other tissues examined, α-Gustducin most closely resembles the
transducins (the rod and cone photoreceptor G proteins), suggesting that gustducin's role in
taste transduction is analogous to that of transducin in light transduction.
Gustducin messenger RNA is expressed in taste buds of all taste papillae (circumvallate,
foliate and fungiform); it is not expressed in non-sensory portions of the tongue, nor is it
expressed in the other tissues examined, α-Gustducin most closely resembles the
transducins (the rod and cone photoreceptor G proteins), suggesting that gustducin's role in
taste transduction is analogous to that of transducin in light transduction.
Abstract
A novel G protein α-subunit (α-gustducin) has been identified and cloned from taste tissue, α-Gustducin messenger RNA is expressed in taste buds of all taste papillae (circumvallate, foliate and fungiform); it is not expressed in non-sensory portions of the tongue, nor is it expressed in the other tissues examined, α-Gustducin most closely resembles the transducins (the rod and cone photoreceptor G proteins), suggesting that gustducin's role in taste transduction is analogous to that of transducin in light transduction.
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