Interleukin-23 and TH17 cells in transplantation immunity: does 23+ 17 equal rejection?
Y Chen, KJ Wood - Transplantation, 2007 - journals.lww.com
Y Chen, KJ Wood
Transplantation, 2007•journals.lww.comAbstract Interleukin-23 (IL-23) and the recently discovered Th17 cells have been implicated
in the pathogenesis of autoimmune diseases. This review will discuss current understanding
of T-cell subsets in transplantation immunity and will explore the role of IL-23 and Th17 cells
in allograft rejection, tolerance, and ischemia reperfusion injury.
in the pathogenesis of autoimmune diseases. This review will discuss current understanding
of T-cell subsets in transplantation immunity and will explore the role of IL-23 and Th17 cells
in allograft rejection, tolerance, and ischemia reperfusion injury.
Abstract
Interleukin-23 (IL-23) and the recently discovered Th17 cells have been implicated in the pathogenesis of autoimmune diseases. This review will discuss current understanding of T-cell subsets in transplantation immunity and will explore the role of IL-23 and Th17 cells in allograft rejection, tolerance, and ischemia reperfusion injury.
Lippincott Williams & Wilkins