Recruitment of osteoclasts in the mandibular condyle of growing osteopetrotic (op/op) mice after a single injection of macrophage colony-stimulating factor
T Kawata, S Kawasoko, M Kaku, T Fujita… - Archives of oral …, 1999 - Elsevier
The purpose was to elucidate histological changes in the mandibular condyle and ramus in
growing osteopetrotic (op/op) mice after a single injection of macrophage colony-stimulating
factor (M-CSF). M-CSF (5μg) was injected into 6-, 11-, 26-, 56-and 86-day-old op/op mice,
and the mice were killed 4 days after the injection. In normal mice, the condyle was
substantially wider than the ramus beneath it, and enlargement and ossification of the
condyle occurred after weaning. These changes were not found in the uninjected and …
growing osteopetrotic (op/op) mice after a single injection of macrophage colony-stimulating
factor (M-CSF). M-CSF (5μg) was injected into 6-, 11-, 26-, 56-and 86-day-old op/op mice,
and the mice were killed 4 days after the injection. In normal mice, the condyle was
substantially wider than the ramus beneath it, and enlargement and ossification of the
condyle occurred after weaning. These changes were not found in the uninjected and …