Lymphosarcoma: virus-induced thymic-independent disease in mice
HT Abelson, LS Rabstein - Cancer research, 1970 - AACR
HT Abelson, LS Rabstein
Cancer research, 1970•AACRA new murine oncogenic virus has been isolated which induces solid lymphoid tumors
within a short latent period. A unique feature of this disease is the lack of thymic involvement.
Thymic-independent tumor induction distinguishes this virus from the other experimental
murine lymphoid leukemia viruses. In addition, massive meningeal tumors, a myelocytic
leukemoid reaction, and no evidence of a disseminated leukemia constitute this disease
syndrome.
within a short latent period. A unique feature of this disease is the lack of thymic involvement.
Thymic-independent tumor induction distinguishes this virus from the other experimental
murine lymphoid leukemia viruses. In addition, massive meningeal tumors, a myelocytic
leukemoid reaction, and no evidence of a disseminated leukemia constitute this disease
syndrome.
Summary
A new murine oncogenic virus has been isolated which induces solid lymphoid tumors within a short latent period. A unique feature of this disease is the lack of thymic involvement. Thymic-independent tumor induction distinguishes this virus from the other experimental murine lymphoid leukemia viruses. In addition, massive meningeal tumors, a myelocytic leukemoid reaction, and no evidence of a disseminated leukemia constitute this disease syndrome.
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