Fibroblast growth factor signaling during early vertebrate development
RT Bottcher, C Niehrs - Endocrine reviews, 2005 - academic.oup.com
RT Bottcher, C Niehrs
Endocrine reviews, 2005•academic.oup.comFibroblast growth factors (FGFs) have been implicated in diverse cellular processes
including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and
proliferation. This review presents our current understanding on the roles of FGF signaling,
the pathways employed, and its regulation. We focus on FGF signaling during early
embryonic processes in vertebrates, such as induction and patterning of the three germ
layers as well as its function in the control of morphogenetic movements.
including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and
proliferation. This review presents our current understanding on the roles of FGF signaling,
the pathways employed, and its regulation. We focus on FGF signaling during early
embryonic processes in vertebrates, such as induction and patterning of the three germ
layers as well as its function in the control of morphogenetic movements.
Fibroblast growth factors (FGFs) have been implicated in diverse cellular processes including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and proliferation. This review presents our current understanding on the roles of FGF signaling, the pathways employed, and its regulation. We focus on FGF signaling during early embryonic processes in vertebrates, such as induction and patterning of the three germ layers as well as its function in the control of morphogenetic movements.
Oxford University Press