Recognition of fungal pathogens by Toll-like receptors

MG Netea, JWM Van der Meer, BJ Kullberg - Immunology of Fungal …, 2007 - Springer
Toll-like receptors (TLRs) have been identified as a major class of pattern-recognition
receptors. Recognition of pathogen-associated molecular patterns (PAMPs) by TLRs, either
alone or in heterodimerization with other TLR or non-TLR receptors, induces signals
responsible for the activation of innate immune response. Recent studies have
demonstrated a crucial involvement of TLRs in the recognition of fungal pathogens such as
Candida albicans, Aspergillus fumigatus and Cryptococcus neoformans. By studying fungal …

Recognition of fungal pathogens by toll-like receptors

MG Netea, G Ferwerda… - Current …, 2006 - ingentaconnect.com
Toll-like receptors (TLRs) have been identified as a major class of pattern-recognition
receptors. Recognition of pathogen-associated molecular patterns (PAMPs) by TLRs, either
alone or in heterodimerization with other TLR or non-TLR receptors, induces signals
responsible for the activation of innate immune response. Recent studies have
demonstrated a crucial involvement of TLRs in the recognition of fungal pathogens such as
Candida albicans, Aspergillus fumigatus and Cryptococcus neoformans. By studying fungal …