Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume …

O Szentirmai, CH Baker, N Lin, S Szucs… - …, 2006 - journals.lww.com
OBJECTIVE: Outcome studies in rodent tumor models rely on both histological and
noninvasive study end points. Intracranial models require special tools to observe tumor
growth over time noninvasively, such as magnetic resonance imaging (MRI), computed
tomographic scanning, or cranial window techniques. These techniques share
disadvantages in terms of cost, technical expertise required, and overall animal throughput
for analysis. In this report, we sought to validate the use of the relatively newer technique of …