[HTML][HTML] Multiparameter immune profiling of operational tolerance in liver transplantation
M Martínez-Llordella, I Puig-Pey, G Orlando… - American Journal of …, 2007 - Elsevier
Immunosuppressive drugs can be completely withdrawn in up to 20% of liver transplant
recipients, commonly referred to as 'operationally'tolerant. Immune characterization of these
patients, however, has not been performed in detail, and we lack tests capable of identifying
tolerant patients among recipients receiving maintenance immunosuppression. In the
current study we have analyzed a variety of biological traits in peripheral blood of
operationally tolerant liver recipients in an attempt to define a multiparameter 'fingerprint'of …
recipients, commonly referred to as 'operationally'tolerant. Immune characterization of these
patients, however, has not been performed in detail, and we lack tests capable of identifying
tolerant patients among recipients receiving maintenance immunosuppression. In the
current study we have analyzed a variety of biological traits in peripheral blood of
operationally tolerant liver recipients in an attempt to define a multiparameter 'fingerprint'of …