CD45RC− γδ+ T-cell infiltration is associated with immunologic unresponsiveness induced by prior donor-specific blood transfusion in rat hepatic allografts
K Okabe, Y Yamaguchi, E Takai, H Ohshiro, JL Zhang… - Hepatology, 2001 - Elsevier
Little is known regarding the role of γδ+ T cells in organ transplantation. We previously
reported that immunologic unresponsiveness is induced by prior donor-specific blood
transfusion (DST) in rat hepatic allografts. We investigated the phenotype and distribution of
γδ+ T cells in the hepatic allograft, spleen, and peripheral blood of recipient rats with
immunologic unresponsiveness induced by DST. γδ+ T cells were enumerated in allograft
livers and spleens by immunostaining and in blood by flow cytometric analysis. The …
reported that immunologic unresponsiveness is induced by prior donor-specific blood
transfusion (DST) in rat hepatic allografts. We investigated the phenotype and distribution of
γδ+ T cells in the hepatic allograft, spleen, and peripheral blood of recipient rats with
immunologic unresponsiveness induced by DST. γδ+ T cells were enumerated in allograft
livers and spleens by immunostaining and in blood by flow cytometric analysis. The …