Cultured olfactory ensheathing cells express nerve growth factor, brain-derived neurotrophic factor, glia cell line-derived neurotrophic factor and their receptors

E Woodhall, AK West, MI Chuah - Molecular brain research, 2001 - Elsevier
In the primary olfactory pathway axons of olfactory neurons (ONs) are accompanied by
ensheathing cells (ECs) as the fibres course towards the olfactory bulb. Ensheathing cells
are thought to play an important role in promoting and guiding olfactory axons to their
appropriate target. In recent years, studies have shown that transplants of ECs into lesions in
the central nervous system (CNS) are able to stimulate the growth of axons and in some
cases restore functional connections. In an attempt to identify a possible mechanism …