Simian immunodeficiency virus model of HIV induced central nervous system dysfunction

EME Burudi, HS Fox - Advances in virus research, 2001 - Elsevier
Publisher Summary This chapter discusses the advances that have been made in the
development and refinement of the simian immunodeficiency virus (SIV) model of human
immunodeficiency virus (HIV) dementia, and its contribution to the understanding and
management of the acquired immunodeficiency syndrome (AIDS) dementia complex (ADC)
in humans. The SIV and the virus HIV are primate lentiviruses that have great genomic,
structural, and virologic similarities. SIVs have been isolated from the different genera of …