Hereditary sensory neuropathy has been considered a dominant trait, but a recessive
transmission has been suggested in a few reports. The segregation ratio in those sibships
having normal parents was 0.26, and the rate of parental consanguinity was greatly
elevated. In sibships with one affected parent, the ratio was 0.50 for the boys but less for the
girls, and the parents were unrelated. These findings indicate that recessive inheritance is
applicable in the former group, while cases in the latter group are inherited dominantly with …