Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145: II. Expression in situ in lymphoid and nonlymphoid tissues
MD Witmer-Pack, WJ Swiggard, A Mirza, K Inaba… - Cellular …, 1995 - Elsevier
The rat monoclonal antibody NLDC-145, which has been utilized as a marker for mouse
dendritic cells in numerous studies, binds an antigen that is more broadly distributed. This
antigen is a unique 205-kDa integral membrane glycoprotein called DEC-205, which we
have recently purified in quantities sufficient for basic biochemical studies, N-terminal
sequencing, and immunization of rabbits. In cytofluorographic experiments, both the new
polyclonal antibody and the original monoclonal detected DEC-205 on many classes of …
dendritic cells in numerous studies, binds an antigen that is more broadly distributed. This
antigen is a unique 205-kDa integral membrane glycoprotein called DEC-205, which we
have recently purified in quantities sufficient for basic biochemical studies, N-terminal
sequencing, and immunization of rabbits. In cytofluorographic experiments, both the new
polyclonal antibody and the original monoclonal detected DEC-205 on many classes of …