Lipoprotein distribution and biological variation of 24S-and 27-hydroxycholesterol in healthy volunteers

I Burkard, A von Eckardstein, G Waeber… - Atherosclerosis, 2007 - Elsevier
24S-and 27-hydroxycholesterol are obligatory intermediates of cholesterol catabolism and
play an important role in the maintenance of whole-body cholesterol homeostasis. Using an
HPLC–MS method for oxysterol quantification, the distribution of esterified and unesterified
oxysterols in lipoprotein subfractions as well as the influence of daytime, food intake and
menstrual cycle on oxysterol concentrations were investigated in healthy volunteers.
Moreover, reference intervals for 24S-and 27-hydroxycholesterol in plasma as well as the …