Progesterone supplementation to prevent recurrent miscarriage and to reduce implantation failure in assisted reproduction cycles

LG Nardo, HN Sallam - Reproductive biomedicine online, 2006 - Elsevier
Implantation failure has been questioned for many cases of recurrent miscarriage and
unsuccessful assisted reproduction. The exact cause of implantation failure is not known, but
luteal phase defect is encountered in many of these cases. Consequently, women with
recurrent miscarriages have been treated with progesterone supplementation with various
degrees of success, and a recent meta-analysis has shown trends for improved live birth
rates in those women. Progesterone probably acts as an immunological suppressant …