Sickle cell nephropathy

P Saborio, JI Scheinman - Journal of the American Society of …, 1999 - journals.lww.com
The presence of renal failure in sickle cell disease (SCD) ranges from 5 to 18% of the total
population of SCD patients (1). Powars et al.(2), in a prospective, case-control study of
patients with SCD compared with sickle cell hemoglobin C patients, documented 31 (4.2%)
patients affected by renal failure. The median age at the time of renal failure was 23.1 yr.
Survival time was 4 yr with a median age of death of 27 yr after the diagnosis of end-stage
renal disease (ESRD) in spite of dialysis treatment. Proteinuria, hypertension, severe …