Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray
CY Chiu, AA Alizadeh, S Rouskin… - Journal of clinical …, 2007 - Am Soc Microbiol
CY Chiu, AA Alizadeh, S Rouskin, JD Merker, E Yeh, S Yagi, D Schnurr, BK Patterson…
Journal of clinical microbiology, 2007•Am Soc MicrobiolABSTRACT A pan-virus DNA microarray (Virochip) was used to detect a human
metapneumovirus (hMPV) strain associated with a critical respiratory tract infection in an
elderly adult with chronic lymphocytic leukemia. This infection had previously eluded
diagnosis despite extensive microbiological testing for possible etiologic agents. The
patient's hMPV strain did not grow in viral culture, and only one of five specific reverse
transcription-PCR assays for hMPV was positive.
metapneumovirus (hMPV) strain associated with a critical respiratory tract infection in an
elderly adult with chronic lymphocytic leukemia. This infection had previously eluded
diagnosis despite extensive microbiological testing for possible etiologic agents. The
patient's hMPV strain did not grow in viral culture, and only one of five specific reverse
transcription-PCR assays for hMPV was positive.
Abstract
A pan-virus DNA microarray (Virochip) was used to detect a human metapneumovirus (hMPV) strain associated with a critical respiratory tract infection in an elderly adult with chronic lymphocytic leukemia. This infection had previously eluded diagnosis despite extensive microbiological testing for possible etiologic agents. The patient's hMPV strain did not grow in viral culture, and only one of five specific reverse transcription-PCR assays for hMPV was positive.
American Society for Microbiology