Effects of the long-term use of depot medroxyprogesterone acetate as hormonal contraceptive on bone mineral density and biochemical markers of bone remodeling
M Shaarawy, SY El-Mallah, S Seoudi, M Hassan… - Contraception, 2006 - Elsevier
PURPOSE AND METHOD: Our objective is to evaluate the effects of the long-term use of
depot medroxyprogesterone acetate (DMPA) as a method of contraception on bone mineral
density (BMD) and bone remodeling. Forty women (21–44 years old) who used DMPA for
contraception for< 1, 1–2 and> 5 years, in addition to 20 age-matched healthy women
(nonusers), participated in this study. Lumbar spine BMD (LS-BMD) was measured by dual-
energy X-ray absorptionmetry. Serum osteocalcin (OC), a bone formation marker, was …
depot medroxyprogesterone acetate (DMPA) as a method of contraception on bone mineral
density (BMD) and bone remodeling. Forty women (21–44 years old) who used DMPA for
contraception for< 1, 1–2 and> 5 years, in addition to 20 age-matched healthy women
(nonusers), participated in this study. Lumbar spine BMD (LS-BMD) was measured by dual-
energy X-ray absorptionmetry. Serum osteocalcin (OC), a bone formation marker, was …