The negative regulatory roles of suppressor of cytokine signaling proteins in myeloid signaling pathways
S Wormald, DJ Hilton - Current opinion in hematology, 2007 - journals.lww.com
S Wormald, DJ Hilton
Current opinion in hematology, 2007•journals.lww.comSuppressor of cytokine signaling proteins have pivotal roles in attenuating cytokine and toll-
like receptor signaling in myeloid cells. Understanding how defective suppressor of cytokine
signaling activity contributes to inflammatory and malignant disease promises to create
significant new therapeutic opportunities.
like receptor signaling in myeloid cells. Understanding how defective suppressor of cytokine
signaling activity contributes to inflammatory and malignant disease promises to create
significant new therapeutic opportunities.
Summary
Suppressor of cytokine signaling proteins have pivotal roles in attenuating cytokine and toll-like receptor signaling in myeloid cells. Understanding how defective suppressor of cytokine signaling activity contributes to inflammatory and malignant disease promises to create significant new therapeutic opportunities.
Lippincott Williams & Wilkins