Hypospadias and endocrine disruption: is there a connection?

LS Baskin, K Himes, T Colborn - Environmental health …, 2001 - ehp.niehs.nih.gov
Hypospadias is one of the most common congenital anomalies in the United States,
occurring in approximately 1 in 250 newborns or roughly 1 in 125 live male births. It is the
result of arrested development of the urethra, foreskin, and ventral surface of the penis
where the urethral opening may be anywhere along the shaft, within the scrotum, or in the
perineum. The only treatment is surgery. Thus, prevention is imperative. To accomplish this,
it is necessary to determine the etiology of hypospadias, the majority of which have been …