Testosterone, dihydrotestosterone and estradiol-17β levels in maternal and fetal plasma and in fetal testes in the rat

R Habert, R Picon - Journal of steroid biochemistry, 1984 - Elsevier
In Sherman rats testosterone, dihydrotestosterone (DHT) and estradiol-17β levels were
measured in maternal and fetal plasma of both sexes during the last 5 days of gestation and
in the fetal testes from day 14.5 of pregnancy using celite microcolumn chromatography and
radioimmunoassay. All the plasma testosterone concentrations in males were at least 4
times higher than in their female littermates. In male fetuses, levels of plasma testosterone
were maximum on day 18.5 (mean= 1.42 ng/ml) and declined thereafter (mean= 0.85 ng/ml …