Enhancement of DNA vaccine potency in rhesus macaques by electroporation
G Otten, M Schaefer, B Doe, H Liu, I Srivastava… - Vaccine, 2004 - Elsevier
Vaccine, 2004•Elsevier
The potency of an HIV DNA vaccine was enhanced in rhesus macaques by in vivo
electroporation, as judged by increased onset, magnitude and duration of antibody and cell-
mediated immune responses against both components of a combination Gag and Env
vaccine. These data demonstrate the utility of the electroporation technology for use in large
animals.
electroporation, as judged by increased onset, magnitude and duration of antibody and cell-
mediated immune responses against both components of a combination Gag and Env
vaccine. These data demonstrate the utility of the electroporation technology for use in large
animals.
The potency of an HIV DNA vaccine was enhanced in rhesus macaques by in vivo electroporation, as judged by increased onset, magnitude and duration of antibody and cell-mediated immune responses against both components of a combination Gag and Env vaccine. These data demonstrate the utility of the electroporation technology for use in large animals.
Elsevier