Genomic instability within tumor stroma and clinicopathological characteristics of sporadic primary invasive breast carcinoma
K Fukino, L Shen, A Patocs, GL Mutter, C Eng - Jama, 2007 - jamanetwork.com
ContextThat genomic alterations occur in both the epithelium and stroma of sporadic breast
cancers has been documented by several groups. However, whether these
microenvironmental alterations relate to clinicopathological features is unknown.
ObjectiveTo analyze the relationship between stromal genomic alterations and presenting
clinicopathological features in sporadic breast cancer. Design, Setting, and ParticipantsA
retrospective cross-sectional analysis of DNA from the epithelium and stroma of 220 primary …
cancers has been documented by several groups. However, whether these
microenvironmental alterations relate to clinicopathological features is unknown.
ObjectiveTo analyze the relationship between stromal genomic alterations and presenting
clinicopathological features in sporadic breast cancer. Design, Setting, and ParticipantsA
retrospective cross-sectional analysis of DNA from the epithelium and stroma of 220 primary …