Allergen rush immunotherapy increases interleukin (IL)-12 production and IL-12 receptor β2 chain expression in patients with allergic asthma
T Tazaki, K Minoguchi, T Yokoe, N Oda, T Hashimoto… - Cellular …, 2004 - Elsevier
Interleukin (IL)-12 production and IL-12 receptor (IL-12R) β2 chain expression were
investigated in patients with allergic asthma successfully treated with rush immunotherapy
(RIT) and control patients with mild allergic asthma. Peripheral blood mononuclear cells
(PBMCs) were stimulated with Dermatophagoides farinae (Der f), and production of
cytokines was measured. Furthermore, the effects of cytokines on IL-12R β2 chain
expression on CD4+ T cells were investigated. Production by PBMCs of IL-12 and IFN-γ was …
investigated in patients with allergic asthma successfully treated with rush immunotherapy
(RIT) and control patients with mild allergic asthma. Peripheral blood mononuclear cells
(PBMCs) were stimulated with Dermatophagoides farinae (Der f), and production of
cytokines was measured. Furthermore, the effects of cytokines on IL-12R β2 chain
expression on CD4+ T cells were investigated. Production by PBMCs of IL-12 and IFN-γ was …