[HTML][HTML] Angiogenesis in the corpus luteum
HM Fraser, C Wulff - Reproductive Biology and Endocrinology, 2003 - Springer
The corpus luteum (CL) is a site of intense angiogenesis. Within a short period, this is
followed either by controlled regression of the microvascular tree in the non-fertile cycle, or
maintenance and stabilisation of the new vasculature a conceptual cycle. The molecular
regulation of these diverse aspects is examined. The CL provides a unique model system in
which to study the cellular and molecular regulation of angiogenesis. Vascular endothelial
growth factor (VEGF) has been found to have a major role in the CL. By targeting its action at …
followed either by controlled regression of the microvascular tree in the non-fertile cycle, or
maintenance and stabilisation of the new vasculature a conceptual cycle. The molecular
regulation of these diverse aspects is examined. The CL provides a unique model system in
which to study the cellular and molecular regulation of angiogenesis. Vascular endothelial
growth factor (VEGF) has been found to have a major role in the CL. By targeting its action at …
Angiogenesis in the corpus luteum of early pregnancy in the marmoset and the effects of vascular endothelial growth factor immunoneutralization on establishment of …
AJ Rowe, KD Morris, R Bicknell… - Biology of …, 2002 - academic.oup.com
This study investigated vascular and molecular changes in the corpus luteum (CL) of early
pregnancy in the marmoset. Ovaries were studied on Days 21 (n= 6) and 28 (n= 6) of
pregnancy and compared with corpora lutea from Day 21 (late luteal) of the nonconception
cycle (n= 8). Endothelial cell proliferation was measured by immunocytochemical detection
of incorporated bromodeoxyuridine. Endothelial cell and pericyte area were assessed by
quantitative immunocytochemistry for CD31 and α-smooth muscle actin, respectively …
pregnancy in the marmoset. Ovaries were studied on Days 21 (n= 6) and 28 (n= 6) of
pregnancy and compared with corpora lutea from Day 21 (late luteal) of the nonconception
cycle (n= 8). Endothelial cell proliferation was measured by immunocytochemical detection
of incorporated bromodeoxyuridine. Endothelial cell and pericyte area were assessed by
quantitative immunocytochemistry for CD31 and α-smooth muscle actin, respectively …