T‐targets: clues to understanding the functions of T‐box proteins
M Tada, JC Smith - Development, growth & differentiation, 2001 - Wiley Online Library
M Tada, JC Smith
Development, growth & differentiation, 2001•Wiley Online LibraryMembers of the T‐box gene family have been identified in both vertebrates and
invertebrates, where they play key roles in the regulation of embryonic development, and
particularly in morphogenesis and the assignment of cell fate. T‐box proteins act as
transcription factors which regulate the expression of downstream effector genes. This
review focuses on the identification of T‐box target genes and the basis of T‐box functional
specificity.
invertebrates, where they play key roles in the regulation of embryonic development, and
particularly in morphogenesis and the assignment of cell fate. T‐box proteins act as
transcription factors which regulate the expression of downstream effector genes. This
review focuses on the identification of T‐box target genes and the basis of T‐box functional
specificity.
Members of the T‐box gene family have been identified in both vertebrates and invertebrates, where they play key roles in the regulation of embryonic development, and particularly in morphogenesis and the assignment of cell fate. T‐box proteins act as transcription factors which regulate the expression of downstream effector genes. This review focuses on the identification of T‐box target genes and the basis of T‐box functional specificity.
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