Use of recombinant congenic strains in mapping disease-modifying genes
J Mullerova, P Hozak - Physiology, 2004 - journals.physiology.org
J Mullerova, P Hozak
Physiology, 2004•journals.physiology.orgPrevious research studies have established much information about single-gene diseases.
However, other genes also influencing the outcome of a disease and genes involved in
complex disease remain largely unknown. Here we report on recombinant congenic strains
of mice, a powerful tool for genetic dissection of a complex trait.
However, other genes also influencing the outcome of a disease and genes involved in
complex disease remain largely unknown. Here we report on recombinant congenic strains
of mice, a powerful tool for genetic dissection of a complex trait.
Previous research studies have established much information about single-gene diseases. However, other genes also influencing the outcome of a disease and genes involved in complex disease remain largely unknown. Here we report on recombinant congenic strains of mice, a powerful tool for genetic dissection of a complex trait.
American Physiological Society