[PDF][PDF] Combination of epidermal growth factor receptor targeted therapy with radiation therapy for malignant gliomas

S Krishnan, RD Rao, CD James, JN Sarkaria - Front Biosci, 2003 - researchgate.net
S Krishnan, RD Rao, CD James, JN Sarkaria
Front Biosci, 2003researchgate.net
Introduction 3. Relevance of EGFR in malignant gliomas 3.1. Alterations of EGFR in gliomas
3.2. Overexpression of EGFR 3.3. Common EGFR mutations 3.4. Correlation with
gliogenesis 4. Strategies for targeting EGFR 4.1. Monoclonal antibodies 4.2. Tyrosine kinase
inhibitors 5. Combined radiation and EGFR inhibitor therapy: mechanisms of action 5.1.
Intrinsic Radiosensitivity
Abstract
Introduction 3. Relevance of EGFR in malignant gliomas 3.1. Alterations of EGFR in gliomas 3.2. Overexpression of EGFR 3.3. Common EGFR mutations 3.4. Correlation with gliogenesis 4. Strategies for targeting EGFR 4.1. Monoclonal antibodies 4.2. Tyrosine kinase inhibitors 5. Combined radiation and EGFR inhibitor therapy: mechanisms of action 5.1. Intrinsic Radiosensitivity
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