[HTML][HTML] The use of genetically altered mice for breast cancer prevention studies
C Kavanaugh, JE Green - The Journal of nutrition, 2003 - Elsevier
Chemoprevention through nutritional and dietary changes may offer an important means of
inhibiting the development and progression of breast cancer, which would have a major
impact on public health. Studies to assess the efficacy of potential chemopreventive
compounds are difficult to perform in large human populations, whereas the use of
genetically engineered mice (GEM) for preclinical testing offers several advantages. GEM
models can be utilized to assess the inhibitory effects of nutritional and chemopreventive …
inhibiting the development and progression of breast cancer, which would have a major
impact on public health. Studies to assess the efficacy of potential chemopreventive
compounds are difficult to perform in large human populations, whereas the use of
genetically engineered mice (GEM) for preclinical testing offers several advantages. GEM
models can be utilized to assess the inhibitory effects of nutritional and chemopreventive …