Mouse models of prostate carcinogenesis

C Abate-Shen, MM Shen - Trends in genetics, 2002 - cell.com
Trends in genetics, 2002cell.com
In recent years, numerous mouse models have been generated that recapitulate salient
features of prostate carcinogenesis in humans. Here we review progress in the generation
and validation of mouse models for prostate cancer, discuss current limitations of these
models, and highlight directions of future research.
Abstract
In recent years, numerous mouse models have been generated that recapitulate salient features of prostate carcinogenesis in humans. Here we review progress in the generation and validation of mouse models for prostate cancer, discuss current limitations of these models, and highlight directions of future research.
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