The peroxisome proliferator activated receptorφ2 (PPARφ2) Pro12Ala variant: lack of association with type 2 diabetes in obese and non obese Tunisian patients
KZ Bouassida, L Chouchane, K Jellouli, S Cherif… - Diabetes & …, 2005 - Elsevier
OBJECTIVES: Peroxisome proliferator activated receptorφ2 (PPARφ2) is a nuclear receptor
that regulates adipocyte differentiation, lipid metabolism and probably insulin sensitivity.
There have been several reports on the relationship between the PPARφ2 Pro12Ala
genotype and the development of obesity or type 2 diabetes. We designed a case-controlled
study to investigate the potential association of the genetic variation of the PPARφ2 gene
with type 2 diabetes in Tunisians. METHODS: We used the polymerase chain reaction and …
that regulates adipocyte differentiation, lipid metabolism and probably insulin sensitivity.
There have been several reports on the relationship between the PPARφ2 Pro12Ala
genotype and the development of obesity or type 2 diabetes. We designed a case-controlled
study to investigate the potential association of the genetic variation of the PPARφ2 gene
with type 2 diabetes in Tunisians. METHODS: We used the polymerase chain reaction and …