[HTML][HTML] Ubiquitination for activation: New directions in the NF-κB roadmap
OT Lynch, M Gadina - Molecular interventions, 2004 - triggered.edina.clockss.org
Interactions between antigens and T cell receptors (TCRs) stimulate several signaling
cascades that activate numerous transcription factors including nuclear factor of activated T
cells (NFAT), Activator protein–1 (AP-1), Ets, and nuclear factor–kappa B (NF-κB). The
activity of the NF-κB family is also induced by other factors such as cytokines or tumor
necrosis factor (TNF) family members, making NF-κB one of the most studied transcription
factors in the immune system. The mammalian NF-κB family consists of many members …
cascades that activate numerous transcription factors including nuclear factor of activated T
cells (NFAT), Activator protein–1 (AP-1), Ets, and nuclear factor–kappa B (NF-κB). The
activity of the NF-κB family is also induced by other factors such as cytokines or tumor
necrosis factor (TNF) family members, making NF-κB one of the most studied transcription
factors in the immune system. The mammalian NF-κB family consists of many members …